Each of the 54 digital pins on the Arduino 2560 Mega can be used as an input or output, using pinMode(), digitalWrite(), and digitalRead() functions. They operate at 5 volts. Each pin can provide or receive a maximum of 40 mA and has an internal pull-up resistor (disconnected by default) of 20-50 kOhms.
In addition, some pins have specialized functions:
Serial: 0 (RX) and 1 (TX);
Serial 1: 19 (RX) and 18 (TX);
Serial 2: 17 (RX) and 16 (TX);
Serial 3: 15 (RX) and 14 (TX).
Used to receive (RX) and transmit (TX) TTL serial data. Pins 0 and 1 are also connected to the corresponding pins of the ATmega16U2 USB-to-TTL Serial chip.
External Interrupts: 2 (interrupt 0), 3 (interrupt 1), 18 (interrupt 5), 19 (interrupt 4), 20 (interrupt 3), and 21 (interrupt 2). These pins can be configured to trigger an interrupt on a low value, a rising or falling edge, or a change in value. See the attachInterrupt() function for details.
PWM: 2 to 13 and 44 to 46. Provide 8-bit PWM output with the analogWrite() function.
SPI: 50 (MISO), 51 (MOSI), 52 (SCK), 53 (SS). These pins support SPI communication using the SPI library. The SPI pins are also broken out on the ICSP header, which is physically compatible with the Uno, Duemilanove and Diecimila.
LED: 13. There is a built-in LED connected to digital pin 13. When the pin is HIGH value, the LED is on, when the pin is LOW, it’s off.
TWI: 20 (SDA) and 21 (SCL). Support TWI communication using the Wire library. Note that these pins are not in the same location as the TWI pins on the Duemilanove or Diecimila.
The Mega2560 has 16 analog inputs, each of which provide 10 bits of resolution (i.e. 1024 different values). By default they measure from ground to 5 volts, though is it possible to change the upper end of their range using the AREF pin and analogReference() function.